CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Solute carrier family 12 member 1 Inhibitor Ethacrynic Acid Family
No. of Seeds 3 No. of Other Members 42
Family Centroid CFAMM00074002 Functional Category Approved Drug with Natural Product
Superfamily Solute carrier Superfamily 6
Class Class 434

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
Ipriflavone family 62 2480
Eprotirome family 11 50
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Prostaglandin G/H synthase 1 Inhibitor (3-chloro-4-propoxy-phe... 2 10
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 2 14
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Protein FimH and Type 1 fimbiral adhesin FimH inhibitor methyl... 1 5
Peroxisome proliferator-activated receptor alpha ligand SureCN... 9 3
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 5 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 2
Transthyretin inhibitor AGN-PC-046XQV family 1 6
Arachidonate 5-lipoxygenase inhibitor SureCN9740792 family 2 6
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 0
NP 7-((6-chloro-4h-benzo[d][1,3]dioxin-8-yl)methoxy)-3-phenyl-... 15 0
NP 3,5-dichloro-4-methoxybenzoate Family 1 4
Putative NP ZINC09486076 Family 56 0
Putative NP ZINC09305195 Family 19 0


External ID

Functional Category

Molecule Name

CFAMM00074002 DAP000748 Approved Drug Ethacrynic acid
CFAMM00074039 CHEMBL1256719 Bioactive R(+)-Butylindazone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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