CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cyclooxygenase Inhibitor Acetaminophen Family
No. of Seeds 2 No. of Other Members 42
Family Centroid CFAMM00075932 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Cyclooxygenase Inhibitor Acetaminophen Superfamily
Class Class 446

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Edrophonium Family 7 40
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Oestrogen receptor and Estrogen receptor beta Ligand 2-(4-hydr... 10 17
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Oestrogen receptor and Estrogen receptor beta Ligand 4-bromo-2... 3 0
Histone deacetylase 1 Inhibitor 7-(4-(dimethylamino)phenoxy)-n... 2 1
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Carbonic anhydrase 14 Inhibitor 4-aminophenol Family 1 6
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 3
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(4... 8 4
Carbonic anhydrase 1 and Carbonic anhydrase 12 inhibitor tert-... 1 0
Neutrophil elastase inhibitor AGN-PC-04S1IE family 1 0
Beta-lactamase inhibitor SureCN7191348 family 1 1
NADP-dependent malic enzyme inhibitor AGN-PC-075ZA5 family 3 0
MAP kinase-activated protein kinase 2 and Lethal factor inhibi... 1 0
NS3 inhibitor AGN-PC-074L2C family 1 3
NP N-(4-hydroxyphenyl)-5-((3as,4s,6ar)-2-oxohexahydro-1h-thien... 2 0
methyl (2S)-2-[[2-(4-hydroxyanilino)-2-oxoacetyl]amino]-4-meth... 1 1


External ID

Functional Category

Molecule Name

CFAMM00075932 DAP000776 Approved Drug Acetaminophen
CFAMM00075914 DNC006015 Investigative Drug AM-404

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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