CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD57
Family Name Reverse transcriptase inhibitor nucleotide adenosine monophosphate analog Tenofovir family
No. of Seeds 4 No. of Other Members 24
Family Centroid CFAMM00009040 Functional Category Approved Drug
Superfamily Reverse transcriptase inhibitor nucleotide adenosine monophosphate analog Tenofovir Superfamily
Class Class 56

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
HIV reverse transcriptase Inhibitor Abacavir Family 3 9
DNA Binder Adenine Family 19 55
Reverse transcriptase Inhibitor Amdoxovir Family 1 2
Adenosine deaminase Inhibitor (2s,3r)-3-(6-amino-9h-purin-9-yl... 4 30
Serine/threonine-protein kinase Chk1 Inhibitor 6-morpholin-4-y... 1 6
Adenosine receptor A1 Ligand Cyclopentyl-(9-ethyl-9h-purin-6-y... 10 3
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-brom... 10 1
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-brom... 1 10
3-hydroxyacyl-CoA dehydrogenase type-2 and Mitogen-activated p... 1 1
Adenosylhomocysteinase inhibitor (E)-4-(6-aminopurin-9-yl)-2-m... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00009040 DAP001430 Approved Drug Tenofovir disoproxil
CFAMM00009054 DAP000060 Approved Drug Adefovir Dipivoxil
CFAMM00009042 DAP000700 Approved Drug Tenofovir
CFAMM00009060 DNC001135 Investigative Drug PMEA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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