CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 4-aminobutyrate aminotransferase, mitochondrial Inhibitor L-alanine Family
No. of Seeds 3 No. of Other Members 23
Family Centroid CFAMM00077276 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily 4-aminobutyrate aminotransferase, mitochondrial Inhibitor L-alanine Superfamily
Class Class 457

Cousin Family NamesSeedsMembers
NMDA receptor Ligand L-glutamic Acid Family 6 32
Plasminogen Inhibitor Aminocaproic Acid Family 4 37
Protein Tat Inhibitor Penicillamine Family 1 2
Fudosteine family 4 34
Growth hormone secretagogue receptor type 1 Ligand SUN-11031 F... 4 10
Gamma-aminobutyric acid A receptor Ligand Gaba Family 2 8
Thymidylate synthase Inhibitor S-oxymethionine Family 1 0
Metabotropic glutamate receptor 8 Ligand 2-amino-4-phosphono-b... 5 13
Sodium- and chloride-dependent GABA transporter 1 Inhibitor 2,... 1 3
Betaine--homocysteine S-methyltransferase 1 inhibitor AGN-PC-0... 1 0
Amino Acids and Derivatives Metabolite L-Isoleucine Family 4 5
Amino Acids and Derivatives Metabolite DL-Homocystine Family 2 3


External ID

Functional Category

Molecule Name

CFAMM00077276 DAP000805 Approved Drug L-Alanine
CFAMM00077258 DNC002986 Investigative Drug D-Alanine
CFAMM00077259 DNC002626 Investigative Drug Alpha-Aminobutyric Acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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