CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD584
Family Name Acetylcholinesterase Inhibitor Pyridostigmine Family
No. of Seeds 5 No. of Other Members 197
Family Centroid CFAMM00077834 Functional Category Approved Drug with Natural Product
Superfamily Acetylcholinesterase Inhibitor Pyridostigmine Superfamily
Class Class 460

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
Neuronal acetylcholine receptor subunit alpha-4 Ligand Isproni... 49 172
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 11
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 ... 4 5
Histamine H3 receptor ligand SureCN4329918 family 4 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 6 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 2
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 4 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 0
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Neuronal acetylcholine receptor subunit alpha-3 and Neuronal a... 4 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 6 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 1
Hormone-sensitive lipase inhibitor AGN-PC-046LTD family 3 8
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 3
2-methylpyridin-3-ol NP 3-hydroxy-2-methylpyridine Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00077834 DAP000809 Approved Drug Pyridostigmine
CFAMM00077827 DNC000868 Investigative Drug Lefaxin
CFAMM00077870 DNC006441 Investigative Drug N,N-dimethyl-2-(pyridin-3-yloxy)ethanamine
CFAMM00077881 DNC011054 Investigative Drug 1-methyl-3-(phenylcarbamoyloxy)pyridinium bromide
CFAMM00077758 DNC006797 Investigative Drug 3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543