CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD588
Family Name Cyclooxygenase Inhibitor Meclofenamic Acid Family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00078186 Functional Category Approved Drug with Human Metabolite
Superfamily Cyclooxygenase and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 448

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Cyclooxygenase Inhibitor Diclofenac Family 6 37
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
New permeability pathways Inhibitor 5-nitro-2-(3-phenylpropyla... 1 13
Glycogen synthase kinase-3 beta Inhibitor I-5 Family 1 8
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Oestrogen receptor and Estrogen receptor beta Ligand 5-chloro-... 1 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Glutamate receptor ionotropic, kainate 1 Ligand 2-(3-(3-bromop... 2 1
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 3
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C8 liga... 2 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Tankyrase-2 inhibitor 3-chloro-4-(4-methyl-2-oxo-1H-quinolin-7... 1 2
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 2
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
Holo-[acyl-carrier-protein] synthase inhibitor AGN-PC-00CGZN f... 1 0
Putative NP ZINC04061910 Family 6 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00078186 DAP000815 Approved Drug Meclofenamic acid
CFAMM00078187 CHEMBL121626 Bioactive tolfenamic acid
CFAMM00078209 DPR000027 Investigative Drug CB1 antagonist
CFAMM00078195 DNC010575 Investigative Drug 2-(3-(3,5-dichlorophenyl)ureido)benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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