CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA topoisomerase 2-beta Inhibitor Nalidixic Acid Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00078213 Functional Category Approved Drug with Human Metabolite
Superfamily DNA topoisomerase 2-beta Inhibitor Nalidixic Acid Superfamily
Class Class 462

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inh... 3 40
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Tubulin beta chain Inhibitor 7-methyl-2-m-tolyl-1h-[1,8]naphth... 7 15
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Tubulin beta chain Inhibitor 2-m-tolyl-1h-[1,8]naphthyridin-4-... 5 2
Glycogen synthase kinase-3 beta inhibitor 5-amino-1-cyclopropy... 3 14


External ID

Functional Category

Molecule Name

CFAMM00078213 DAP000817 Approved Drug Nalidixic Acid
CFAMM00078225 CHEMBL35337 Bioactive Amfonelic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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