CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Histamine receptor Ligand Histamine Phosphate Family
No. of Seeds 6 No. of Other Members 78
Family Centroid CFAMM00086846 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Histamine receptor Ligand Histamine Phosphate Superfamily
Class Class 464

Cousin Family NamesSeedsMembers
Histamine H2 receptor Ligand Cimetidine Family 2 14
Histamine H3 receptor Ligand Cipralisant Family 36 70
Histamine H3 receptor and Histamine H4 receptor Ligand Thioper... 8 12
Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(... 26 80
Carboxypeptidase B2 Inhibitor 6-amino-2-(1h-imidazol-4-yl)-hex... 3 8
Histamine H2 receptor and Histamine H1 receptor ligand N-[N'-[... 1 2
Histamine H3 receptor ligand SureCN7961024 family 2 0
Azoles Metabolite Methylimidazole acetaldehyde Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00086785 DAP001379 Approved Drug Ergotidine
CFAMM00086846 DAP000820 Approved Drug Histamine Phosphate
CFAMM00086810 CHEMBL2067978 Bioactive [3H]Nalpha-methylhistamine
CFAMM00086799 CHEMBL545378 Bioactive (2R)-2-(1H-imidazol-5-yl)propan-1-amine;hydrobromide
CFAMM00086790 CHEMBL1533310 Bioactive Histamine dihydrochloride
CFAMM00086808 DNC000987 Investigative Drug N-alpha-methyl histamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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