CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Alpha-2 adrenergic receptor ligand Clonidine derivative Lofexidine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00012336 Functional Category Approved Drug
Superfamily Alpha-2 adrenergic receptor ligand Clonidine derivative Lofexidine Superfamily
Class Class 60

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand Dexefaroxan Family 11 46
Alpha-2 adrenergic receptor Ligand Idazoxan Family 6 26


External ID

Functional Category

Molecule Name

CFAMM00012336 DAP000064 Approved Drug Lofexidine
CFAMM00012334 CHEMBL1788132 Bioactive Lofexidine hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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