CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Aromatic-L-amino-acid decarboxylase Inhibitor Vitamin B6 Family
No. of Seeds 6 No. of Other Members 13
Family Centroid CFAMM00089916 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Aromatic-L-amino-acid decarboxylase Inhibitor Vitamin B6 Superfamily
Class Class 487

Cousin Family NamesSeedsMembers
4-aminobutyrate aminotransferase, mitochondrial Inhibitor Pyri... 3 16
Citric Acid family 2 58
Cicletanine family 1 7
Alanine racemase Inhibitor Pyridoxyl-n,o-cycloserylamide-5-mon... 1 0
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Histone deacetylase 1 inhibitor 7-[3-fluoro-4-[[3-hydroxy-5-(h... 2 1
Histone deacetylase 1 and D-amino-acid oxidase inhibitor 2,3-D... 1 6
Amino Acids and Derivatives Metabolite 3-Hydroxypicolinic acid... 1 2


External ID

Functional Category

Molecule Name

CFAMM00089916 DAP000869 Approved Drug Vitamin B6
CFAMM00089913 DCL001024 Clinical Trial Drug TRIDMAC
CFAMM00089926 DNCL002966 Clinical Trial Drug Pyridoxamine
CFAMM00089917 DNC002599 Investigative Drug Pyridoxamine-5'-Phosphate
CFAMM00089921 DNC002618 Investigative Drug N-Pyridoxyl-Glycine-5-Monophosphate
CFAMM00089928 DNC002641 Investigative Drug Pyridoxine-5'-Phosphate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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