CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD63
Family Name Beta adrenergic receptor ligand catecholamine group Isoproterenol Family
No. of Seeds 7 No. of Other Members 130
Family Centroid CFAMM00012416 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily adrenergic receptor ligand catecholamine Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Dopamine receptor ligand L-Tyrosine derivative Levodopa Family 4 59
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-2 adrenergic receptor Ligand Oxymetazoline Family 5 4
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Zucapsacin family 7 177
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Muscarinic acetylcholine receptor M1 Ligand GSK573719 Family 2 0
D(2) dopamine receptor Ligand N-0923 Family 6 41
D(3) dopamine receptor Ligand U-99194A Family 7 33
Vernakalant family 1 1
CORT-108297 family 46 44
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 16 27
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Acetylcholinesterase and Cholinesterase Inhibitor N,n'-(1',10'... 12 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 4-hy... 2 13
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Lethal factor Inhibitor N-(3,4,5-trihydroxyphenethyl)oleamide ... 1 3
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
D(2) dopamine receptor and D(1A) dopamine receptor Ligand SK&F... 8 8
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Tubulin beta chain Inhibitor Colchinol Family 3 109
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-01Z... 2 4
D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,... 3 2
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic rec... 2 1
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Mu-type opioid receptor ligand 4-[(2S)-3-[[(2S)-1-(4-hydroxyph... 2 6
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
D(1A) dopamine receptor and D(2) dopamine receptor ligand Biom... 3 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2
Phenylalanine--tRNA ligase alpha subunit inhibitor TCMDC-14030... 1 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 5
Alpha-2A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00012532 DAP000936 Approved Drug Arbutamine
CFAMM00012416 DAP000080 Approved Drug Isoproterenol
CFAMM00012469 DAP000245 Approved Drug Dobutamine
CFAMM00012388 DNAP001469 Approved Drug Dopexamine
CFAMM00012453 DAP000066 Approved Drug Epinephrine
CFAMM00012533 DAP000935 Approved Drug Isoetharine
CFAMM00012442 DNC012803 Investigative Drug 4-(3-Hydroxy-piperidin-3-yl)-benzene-1,2-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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