CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-alpha reductase Inhibitor Azelaic Acid Family
No. of Seeds 11 No. of Other Members 166
Family Centroid CFAMM00090534 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily 5-alpha reductase Inhibitor Azelaic Acid Superfamily
Class Class 494

Cousin Family NamesSeedsMembers
4-aminobutyrate aminotransferase, mitochondrial Inhibitor Diva... 2 28
ETC-1002 family 1 29
Losartan/thioctic Acid family 2 8
Melanocortin receptor 4 Ligand Melanocortin-4 Receptor Antagon... 1 56
Lymphocyte antigen 96 and Toll-like receptor 4 Ligand 3-hydrox... 1 56
Protein kinase C alpha type Inhibitor 1,2-dioctanoyl-sn-glycer... 3 181
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor 9-oc... 2 1
Solute carrier family 22 member 6 Inhibitor Adipate Family 1 8
Solute carrier family 22 member 6 Inhibitor Heptanoate Family 1 4
CAI-1 autoinducer sensor kinase/phosphatase CqsS inhibitor CAI... 4 9
Prelamin-A/C inhibitor ISOPROPYL MYRISTATE family 1 92
Keto-Acids and Derivatives Metabolite Oxoadipic acid Family 2 0
Hydroxy Acids and Derivatives Metabolite 2-Hydroxydecanedioic ... 1 1
Fatty Acids and Conjugates Metabolite 2-Methyladipic acid Family 5 2
Fatty Acids and Conjugates Metabolite Ethyladipic acid Family 4 32
Fatty Alcohol Esters Metabolite Dodecyl propionate Family 14 13
Fatty Acids and Conjugates Metabolite 2-Ethylsuberic acid Family 5 76
Fatty Acid Esters Metabolite 3-Methylbutyl nonanoate Family 5 50
Fatty Acid Esters Metabolite Hexyl hexanoate Family 7 3
Fatty Acid Esters Metabolite Isobutyl enanthate Family 2 0
Macrolides and Analogues Metabolite Ethylene brassylate Family 1 5
Fatty Acids and Conjugates Metabolite Heptylmalonic acid Family 1 6


External ID

Functional Category

Molecule Name

CFAMM00090534 DAP000889 Approved Drug Azelaic Acid
CFAMM00090543 DNC002439 Investigative Drug MYRISTIC ACID
CFAMM00090542 DNC003123 Investigative Drug N-Tridecanoic Acid
CFAMM00090558 DNC003335 Investigative Drug SEBACIC ACID
CFAMM00090654 DNC002746 Investigative Drug Decanoic Acid
CFAMM00090653 DNC002747 Investigative Drug Caprylic acid
CFAMM00090489 DNC009172 Investigative Drug 7,9-tetradecadiynoic acid
CFAMM00090564 DNC002483 Investigative Drug 4-Oxosebacic Acid
CFAMM00090488 DNC009173 Investigative Drug 7,9-octadecadiynoic acid
CFAMM00090544 DNC002438 Investigative Drug Lauric Acid
CFAMM00090415 DNC002568 Investigative Drug Palmitic Acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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