CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD643
Family Name Type-1 angiotensin II receptor Ligand Olmesartan Family
No. of Seeds 13 No. of Other Members 65
Family Centroid CFAMM00090918 Functional Category Approved Drug
Superfamily Type-1 angiotensin II receptor Ligand Olmesartan Superfamily
Class Class 306

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 30
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 25
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Type-1 angiotensin II receptor and Peroxisome proliferator-act... 3 16
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Type-1 angiotensin II receptor ligand 2-propyl-3-[[4-[2-(2H-te... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor ligand AGN-PC-025PHO family 3 21


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00090918 DAP000907 Approved Drug Olmesartan
CFAMM00090909 DAP001412 Approved Drug Olmesartan medoxomil
CFAMM00090925 CHEMBL306924 Bioactive (2-phenylphenyl)methyl 5-ethyl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
CFAMM00090905 CHEMBL309455 Bioactive SureCN2925769
CFAMM00090937 CHEMBL115946 Bioactive SureCN3841141
CFAMM00090923 CHEMBL447182 Bioactive SureCN684076
CFAMM00090889 CHEMBL306473 Bioactive [4-[benzyl(butyl)amino]-4-oxobutyl] 5-ethyl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
CFAMM00090915 CHEMBL116094 Bioactive SureCN7309878
CFAMM00090927 CHEMBL327876 Bioactive 2-butyl-5-(1,1,2,2,2-pentafluoroethyl)-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
CFAMM00090920 CHEMBL320135 Bioactive SureCN683717
CFAMM00090926 CHEMBL306923 Bioactive (4-phenylphenyl)methyl 5-ethyl-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
CFAMM00090892 CHEMBL443269 Bioactive Dup 532

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42884 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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