CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD654
Family Name ATP-sensitive inward rectifier potassium channel 10 Ligand Acetohexamide Family
No. of Seeds 2 No. of Other Members 64
Family Centroid CFAMM00092525 Functional Category Approved Drug
Superfamily ATP-sensitive inward rectifier potassium channel 10 Ligand Acetohexamide Superfamily
Class Class 509

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
DNA Binder Procarbazine Family 8 358
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Chloride channel protein 2 Ligand Acid-activated Omeprazole Fa... 1 1
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Integrin beta-3 Inhibitor L-750034 Family 7 38
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Saccha... 2 13
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 5
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Neprilysin inhibitor AGN-PC-047EOK family 7 4
Neprilysin inhibitor AGN-PC-047EP1 family 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-met... 8 13
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Replication protein E1 inhibitor AC1LAK2U family 3 10
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 10 5
Poly [ADP-ribose] polymerase 1 inhibitor SureCN2769748 family 1 1
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Cannabinoid receptor 2 ligand AC1PDO4X family 2 4
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0
Caspase-3 inhibitor 3-oxo-N-(2-phenylethyl)-1,2-benzothiazole-... 1 3
Lethal(3)malignant brain tumor-like protein 3 and Lethal(3)mal... 1 0
C-C chemokine receptor type 5 ligand AC1NUL29 family 1 0
Bifunctional epoxide hydrolase 2 and Lysosomal alpha-glucosida... 9 3
Secreted frizzled-related protein 1 and Proto-oncogene Wnt-3 i... 2 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00092525 DAP000922 Approved Drug Acetohexamide
CFAMM00092597 DNC009643 Investigative Drug N-(4-sulfamoylphenylethyl)-4-sulfamoylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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