CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD67
Family Name Delta-type opioid receptor ligand opiate analog Codeine Family
No. of Seeds 15 No. of Other Members 184
Family Centroid CFAMM00014249 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily opioid receptor ligand opiate Codeine Buprenorphine Oxymorphone Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Acetylcholinesterase Inhibitor Galantamine Family 4 49
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Nalfurafine Hcl family 33 107
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 18 25
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Delta-type opioid receptor Ligand Longanine Family 3 0
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Tubulin beta chain Inhibitor Colchinol Family 3 109
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Mu-type opioid receptor ligand Morphine-6-glucuronide family 7 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Mu-type opioid receptor and Gastrin/cholecystokinin type B rec... 1 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00014249 DAP000213 Approved Drug Codeine
CFAMM00014353 DNAP001673 Approved Drug Heroin
CFAMM00014314 DAP000071 Approved Drug Morphine
CFAMM00014452 DNC013076 Investigative Drug M3Pr6S
CFAMM00014298 DNC008421 Investigative Drug ORIPAVINE
CFAMM00014386 DNC003327 Investigative Drug Ethylmorphine
CFAMM00014410 DNC013084 Investigative Drug MM3A6S
CFAMM00014451 DNC013077 Investigative Drug M3IBu6S
CFAMM00014416 DNC013082 Investigative Drug DM3A6S
CFAMM00014247 DNC000986 Investigative Drug Nalorphine
CFAMM00014413 DNC013087 Investigative Drug DC6S
CFAMM00014246 DNC013075 Investigative Drug M3A6S
CFAMM00014412 DNC013086 Investigative Drug C6S
CFAMM00014331 DNC008419 Investigative Drug THEBAINE
CFAMM00014453 DNC013078 Investigative Drug M3P6S

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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