CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Calcium-activated potassium channel subunit alpha-1 Ligand Chlorzoxazone Family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00093661 Functional Category Approved Drug with Human Metabolite
Superfamily Calcium-activated potassium channel subunit alpha-1 Ligand Chlorzoxazone Superfamily
Class Class 520

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Oestrogen receptor and Estrogen receptor beta Ligand 5-chloro-... 1 0
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 9
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
Translocator protein inhibitor 2-(5-chloro-2-oxo-1,3-benzoxazo... 1 2
Alpha-1D adrenergic receptor and D(2) dopamine receptor ligand... 3 0
5-hydroxytryptamine receptor 4 ligand 2-(3,5-dimethylpiperidin... 1 2
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 1


External ID

Functional Category

Molecule Name

CFAMM00093661 DAP000952 Approved Drug Chlorzoxazone
CFAMM00093685 CHEMBL301510 Bioactive 2-piperidin-1-ylethyl N-(5-chloro-2-methoxyphenyl)carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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