CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cysteinyl leukotriene receptor 1 Ligand Pranlukast Family
No. of Seeds 21 No. of Other Members 72
Family Centroid CFAMM00095145 Functional Category Approved Drug with Human Metabolite
Superfamily Cysteinyl leukotriene receptor 1 Ligand Pranlukast Superfamily
Class Class 532

Cousin Family NamesSeedsMembers
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 7 0
Cysteinyl leukotriene receptor 1 ligand SureCN7008285 family 12 97
Cysteinyl leukotriene receptor 1 ligand 2-[[3-[[3-methoxy-5-(2... 8 0
Cysteinyl leukotriene receptor 1 ligand 7-[[3-(quinolin-2-ylme... 7 5
Type-1 angiotensin II receptor ligand methyl 2-methyl-6-propyl... 7 10
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Type-1B angiotensin II receptor ligand AGN-PC-040VXR family 6 15
Type-1 angiotensin II receptor ligand 2-[(2-methyl-5,6,7,8-tet... 5 0
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 3


External ID

Functional Category

Molecule Name

CFAMM00095145 DAP000977 Approved Drug Pranlukast
CFAMM00095170 CHEMBL312090 Bioactive SureCN8162439
CFAMM00095218 CHEMBL47662 Bioactive N-[4-oxo-2-(2H-tetrazol-5-yl)-2,3-dihydrochromen-8-yl]-4-(quinolin-2-ylmethoxy)benzamide
CFAMM00095184 CHEMBL354530 Bioactive SureCN8150223
CFAMM00095177 CHEMBL81565 Bioactive SureCN8163608
CFAMM00095203 CHEMBL11350 Bioactive ONO-1078
CFAMM00095169 CHEMBL169790 Bioactive SureCN8157672
CFAMM00095176 CHEMBL311891 Bioactive SureCN6951828
CFAMM00095216 CHEMBL312051 Bioactive SureCN9551221
CFAMM00095182 CHEMBL170191 Bioactive SureCN8157041
CFAMM00095148 CHEMBL354129 Bioactive SureCN8149864
CFAMM00095154 CHEMBL172766 Bioactive SureCN6957886
CFAMM00095181 CHEMBL171021 Bioactive SureCN8157194
CFAMM00095194 CHEMBL171689 Bioactive SureCN8163711
CFAMM00095208 CHEMBL312105 Bioactive SureCN8157577
CFAMM00095147 CHEMBL172889 Bioactive 4-(4-phenylbutoxy)-N-[3-(2H-tetrazol-5-yl)-2,3-dihydro-1,4-benzodioxin-5-yl]benzamide
CFAMM00095166 CHEMBL170959 Bioactive SureCN8159698
CFAMM00095228 CHEMBL285070 Bioactive AGN-PC-002QVR
CFAMM00095207 CHEMBL83447 Bioactive SureCN8163406
CFAMM00095159 CHEMBL83797 Bioactive SureCN8158610
CFAMM00095205 CHEMBL422917 Bioactive SureCN8158631

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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