CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA Binder Adenine Family
No. of Seeds 19 No. of Other Members 55
Family Centroid CFAMM00095544 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily DNA Binder Adenine Superfamily
Class Class 534

Cousin Family NamesSeedsMembers
Reverse transcriptase inhibitor nucleotide adenosine monophosp... 4 24
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
HIV reverse transcriptase Inhibitor Abacavir Family 3 9
Cyclin-dependent kinase 2 Inhibitor Triazolopyrimidine Family 1 3
Adenosine deaminase Inhibitor (2s,3r)-3-(6-amino-9h-purin-9-yl... 4 30
Serine/threonine-protein kinase Chk1 Inhibitor 6-morpholin-4-y... 1 6
Adenosine receptor A1 Ligand Cyclopentyl-(9-ethyl-9h-purin-6-y... 10 3
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-brom... 10 1
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-brom... 1 10
Farnesyl pyrophosphate synthase Inhibitor [2-(6-chloro-purin-9... 2 2
3-hydroxyacyl-CoA dehydrogenase type-2 and Mitogen-activated p... 1 1
Adenosine receptor A2a and Adenosine receptor A3 ligand 5-buty... 1 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor (2S)-2-[[9-p... 5 5
Ribosomal protein S6 kinase alpha-5 and Serine/threonine-prote... 1 2
Adenosylhomocysteinase inhibitor (E)-4-(6-aminopurin-9-yl)-2-m... 3 0
3-(7H-purin-6-ylamino)propanamide NP 3-((9h-purin-6-yl)amino)-... 6 0


External ID

Functional Category

Molecule Name

CFAMM00095544 DAP000982 Approved Drug Adenine
CFAMM00095555 DNC008805 Investigative Drug 9-Ethyl-9H-adenine
CFAMM00095479 DNC010221 Investigative Drug 6-(4-methylpiperazin-1-yl)-9Hpurine
CFAMM00095554 DNC008804 Investigative Drug 8-Bromo-9-methyl-9H-adenine
CFAMM00095569 DNC007394 Investigative Drug 2-chloro-6(methylamino)purine
CFAMM00095559 DNC008809 Investigative Drug 9-Isopropyl-9H-adenine
CFAMM00095532 DNC008827 Investigative Drug 8-Br-adenine
CFAMM00095551 DNC005309 Investigative Drug N*6*-Cyclohexyl-N*2*-ethyl-9H-purine-2,6-diamine
CFAMM00095525 DNC002922 Investigative Drug N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE
CFAMM00095558 DNC008803 Investigative Drug 9-Methyl-9H-purin-6-ylamine
CFAMM00095494 DNC008831 Investigative Drug 9-Butyl-9H-adenine
CFAMM00095517 DNC008833 Investigative Drug 9-Cyclopropyl-9H-adenine
CFAMM00095531 DNC008829 Investigative Drug 7-Isopropyl-7H-adenine
CFAMM00095557 DNC008807 Investigative Drug 9-Propyl-9H-adenine
CFAMM00095516 DNC008830 Investigative Drug 9-(sec-Butyl)-9H-adenine
CFAMM00095530 DNC008828 Investigative Drug 7-Propyl-7H-adenine
CFAMM00095566 DNC010254 Investigative Drug 6-(piperazin-1-yl)-9-propyl-9H-purine
CFAMM00095556 DNC008806 Investigative Drug 8-Bromo-9-ethyl-9H-adenine
CFAMM00095480 DNC010223 Investigative Drug 6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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