CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD694
Family Name DNA Binder purine nucleoside Adenosine analog Nelarabine Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00095592 Functional Category Approved Drug
Superfamily Adenosine receptor, DNA binding purine nucleoside Adenosine analog Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Family 4 11
Bucladesine family 1 1
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
TG-C family 11 208
Reverse transcriptase Inhibitor Amdoxovir Family 1 2
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Selenazole-... 2 1
Adenosylhomocysteinase Inhibitor D-eritadenine Family 2 1
Adenosine deaminase Inhibitor (2s,3r)-3-(6-amino-9h-purin-9-yl... 4 30
Adenosylhomocysteinase Inhibitor 4(z)-(5'-deoxyadenosin-5'-yli... 2 1
3-hydroxyacyl-CoA dehydrogenase type-2 and Mitogen-activated p... 1 1
2-5A-dependent ribonuclease inhibitor [[(2R,3R,4R,5R)-5-(6-ami... 13 25
Adenosine receptor A1 ligand CHEMBL2112106 family 7 7
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00095592 DAP000985 Approved Drug Nelarabine
CFAMM00095588 DNC003224 Investigative Drug 6-O-Phosphoryl Inosine Monophosphate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543