CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD708
Family Name Dopamine receptor ligand norcamphene derivative Fencamfamine Family
No. of Seeds 3 No. of Other Members 41
Family Centroid CFAMM00098150 Functional Category Approved Drug with Natural Product
Superfamily Dopamine receptor ligand norcamphene derivative Fencamfamine, Amine oxidase inhibitor Rasagiline Superfamily
Class Class 90

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Extracellular calcium-sensing receptor ligand Cinacalcet Family 2 30
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Amine oxidase [flavin-containing] B Inhibitor Rasagiline Family 2 11
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Zicronapine family 43 62
Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 4 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand Sure... 2 0
Sodium-dependent dopamine transporter and Sigma non-opioid int... 1 6
5-hydroxytryptamine receptor 1A ligand SureCN8901985 family 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 2 8
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00098150 DAP001007 Approved Drug Fencamfamine
CFAMM00098173 CHEMBL162352 Bioactive (2R,4aS,9aR)-2-(aminomethyl)-N-methyl-1,2,3,4,9,9a-hexahydrofluoren-4a-amine
CFAMM00098138 CHEMBL157931 Bioactive (4aR,9aS)-N-methyl-1,2,3,4,9,9a-hexahydrofluoren-4a-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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