CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD71
Family Name D(2) dopamine receptor ligand phenylpiperazine derivative Aripiprazole family
No. of Seeds 3 No. of Other Members 53
Family Centroid CFAMM00015806 Functional Category Approved Drug
Superfamily D(2) dopamine receptor ligand phenylpiperazine derivative Aripiprazole Superfamily
Class Class 69

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 6
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family 2 0
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2R... 8 9
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 3
Somatostatin receptor type 1 and D(4) dopamine receptor ligand... 9 10
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 7 1
Mitogen-activated protein kinase 14 inhibitor (2R)-2-amino-N-[... 9 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
D(3) dopamine receptor and D(4) dopamine receptor ligand SureC... 3 19
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 2
Metabotropic glutamate receptor 5 ligand AGN-PC-0760YQ family 3 0
Putative NP ZINC04030010 Family 8 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00015806 DAP000076 Approved Drug Aripiprazole
CFAMM00015797 CHEMBL157923 Bioactive 7-[4-[4-(2-chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
CFAMM00015792 DCL000907 Clinical Trial Drug OPC-14523

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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