CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Oestrogen receptor Ligand Mestranol Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00098411 Functional Category Approved Drug with Natural Product
Superfamily Oestrogen receptor Ligand Mestranol Superfamily
Class Class 223

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor ligand steroid Estradiol derivative Fulvest... 3 64
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
Steryl-sulfatase Inhibitor 2-ethylestradiol 3,17-o,o-bis-sulfa... 1 2
Carbonic anhydrase 2 and Steryl-sulfatase Inhibitor 2-methoxye... 2 7
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Estrogen receptor ligand (8S,9R,11S,13S,14S,17S)-11-[4-[2-[2-(... 1 4
Glucocorticoid receptor ligand (8S,11R,13S,14S,17S)-17-hydroxy... 3 8
Progesterone receptor and Glucocorticoid receptor ligand (8S,1... 6 1
Androgen receptor and Estrogen receptor ligand estradiol benzo... 1 29
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-[(3-bromophe... 1 1
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-[(3,4-dichlo... 1 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 1
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
Aldo-keto reductase family 1 member C3 inhibitor (2R,8'R,9'S,1... 1 0
Estradiol 17-beta-dehydrogenase 1 inhibitor SureCN4589665 family 2 4
Steryl-sulfatase inhibitor [(8R,9S,13S,14S)-13-methyl-17-oxo-7... 1 9
Aromatase inhibitor AGN-PC-075LLF family 1 0
Sodium/potassium-transporting ATPase subunit alpha-1 and Sodiu... 1 0
Putative NP ZINC03881930 Family 8 5


External ID

Functional Category

Molecule Name

CFAMM00098411 DAP001014 Approved Drug Mestranol
CFAMM00098410 DAP001016 Approved Drug Quinestrol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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