CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Histamine H1 receptor Ligand Epinastine Family
No. of Seeds 2 No. of Other Members 26
Family Centroid CFAMM00099964 Functional Category Approved Drug
Superfamily Histamine H1 receptor Ligand Epinastine Superfamily
Class Class 562

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Antazoline Family 5 57
D(2) dopamine receptor Ligand Nomifensine Family 6 100
NMDA receptor Ligand Aptiganel Hcl Family 2 82
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
ATP-binding cassette sub-family C member 9 and ATP-sensitive i... 1 2
Beta-lactamase and Prelamin-A/C inhibitor CHEMBL1560571 family 1 5
Cytochrome P450 2C9 and Cytochrome P450 2D6 inhibitor N'-(4-he... 1 0


External ID

Functional Category

Molecule Name

CFAMM00099964 DAP001074 Approved Drug Epinastine
CFAMM00099946 DNC012052 Investigative Drug TRAMAZOLINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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