CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD740
Family Name HIV-1 protease Inhibitor Tipranavir Family
No. of Seeds 25 No. of Other Members 10
Family Centroid CFAMM00100268 Functional Category Approved Drug
Superfamily HIV-1 protease Inhibitor Tipranavir Superfamily
Class Class 566

Cousin Family NamesSeedsMembers
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Pol polyprotein inhibitor AGN-PC-0AAOIM family 4 0
Pol polyprotein inhibitor AC1LADJW family 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00100268 DAP001085 Approved Drug Tipranavir
CFAMM00100267 CHEMBL21405 Bioactive N-[3-[1(R or S)-(4-Hydroxy-2-oxo-6-n-propyl-6(R or S)-phenethyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl]-5-cyanopyridine-2-sulfonamide
CFAMM00100282 CHEMBL116068 Bioactive Tipranavir deriv. 38
CFAMM00100274 CHEMBL353086 Bioactive N-[5-tert-butyl-4-[[4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propan-2-yl-3H-pyran-5-yl]sulfanyl]-2-methylphenyl]pyridine-3-sulfonamide
CFAMM00100253 CHEMBL117389 Bioactive Tipranavir deriv. 37
CFAMM00100266 CHEMBL88964 Bioactive AGN-PC-00IXYB
CFAMM00100281 CHEMBL2111770 Bioactive Tipranavir analog 12
CFAMM00100259 CHEMBL2111769 Bioactive Tipranavir analog 13
CFAMM00100273 CHEMBL222559 Bioactive Tipranavir
CFAMM00100287 CHEMBL16636 Bioactive AGN-PC-0AAPKH
CFAMM00100280 CHEMBL2110205 Bioactive N-[5-tert-butyl-4-[[(2S)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propan-2-yl-3H-pyran-5-yl]sulfanyl]-2-methylphenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide
CFAMM00100258 CHEMBL2111768 Bioactive Tipranavir isomer
CFAMM00100286 CHEMBL2112563 Bioactive Tipranavir isomer
CFAMM00100251 CHEMBL22121 Bioactive AGN-PC-0ABMVD
CFAMM00100264 CHEMBL2092977 Bioactive AC1LAQUX
CFAMM00100257 CHEMBL325454 Bioactive Tipranavir deriv. 35
CFAMM00100271 CHEMBL315121 Bioactive AC1LA760
CFAMM00100285 CHEMBL2112565 Bioactive Tipranavir analog 11
CFAMM00100277 CHEMBL119906 Bioactive AC1LAQVU
CFAMM00100256 CHEMBL169381 Bioactive N-[5-tert-butyl-4-[[4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propan-2-yl-3H-pyran-5-yl]sulfanyl]-2-methylphenyl]pyridine-2-sulfonamide
CFAMM00100284 CHEMBL20846 Bioactive Tipranavir analog 4
CFAMM00100262 CHEMBL332684 Bioactive SureCN6953675
CFAMM00100276 CHEMBL130184 Bioactive AGN-PC-0AAPKM
CFAMM00100255 CHEMBL352485 Bioactive 263842-78-0
CFAMM00100283 CHEMBL276592 Bioactive AC1LAAAE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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