CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family
No. of Seeds 12 No. of Other Members 5
Family Centroid CFAMM00101285 Functional Category Approved Drug
Superfamily Muscarinic acetylcholine receptor ligand Oxyphencyclimine Mepenzolate Oxyphenonium Superfamily
Class Class 474

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid S... 7 16
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Muscarinic acetylcholine receptor Ligand Oxyphencyclimine Family 1 2
Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Beta-lactamase inhibitor CHEMBL1358094 family 1 10


External ID

Functional Category

Molecule Name

CFAMM00101289 DAP001116 Approved Drug Glycopyrrolate
CFAMM00101285 DAP001124 Approved Drug Oxyphenonium
CFAMM00101284 DAP001128 Approved Drug Oxybutynin
CFAMM00101297 CHEMBL142026 Bioactive AGN-PC-075OIJ
CFAMM00101296 CHEMBL142084 Bioactive AC1L1AMI
CFAMM00101288 CHEMBL342839 Bioactive N-Desethyl rac-Benzilonium
CFAMM00101292 CHEMBL140576 Bioactive AGN-PC-075OII
CFAMM00101299 DNCL001925 Clinical Trial Drug MCD-386/glycopyrrolate
CFAMM00101290 DNC000293 Investigative Drug Benactyzine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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