CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family
No. of Seeds 3 No. of Other Members 17
Family Centroid CFAMM00101434 Functional Category Approved Drug with Natural Product
Superfamily Muscarinic acetylcholine receptor M3 Ligand Darifenacin Superfamily
Class Class 579

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Zucapsacin family 7 177
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand DA-5018 Family 14 73
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Cannabinoid receptor 1 Ligand N-(3,5-dimethoxyphenethyl)oleami... 5 49
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Histone deacetylase 4 Inhibitor N-hydroxy-9h-xanthene-9-carbox... 1 0
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 1
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 1 0
5-hydroxytryptamine receptor 1A ligand oxalic acid;(1R,5S)-5-[... 2 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 2 4
Dipeptidyl peptidase 4 inhibitor SureCN5777647 family 1 0
Lysosomal alpha-glucosidase inhibitor MLS000587024 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00101434 DAP001131 Approved Drug Darifenacin
CFAMM00101421 CHEMBL1910845 Bioactive 5-[(3S)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylpentanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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