CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD788
Family Name Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family
No. of Seeds 19 No. of Other Members 117
Family Centroid CFAMM00102329 Functional Category Approved Drug with Human Metabolite
Superfamily Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Superfamily
Class Class 379

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Beta-lactamase Inhibitor M-aminophenylboronic Acid Family 2 16
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-hydr... 3 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-chlo... 2 12
Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phen... 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 2 Inhibitor 3-nitro-benzenesulfonamide Family 3 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-isot... 1 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
Reverse transcriptase Inhibitor 1-nitro-2-(2-nitrophenylsulfon... 3 8
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 2 and Prostaglandin G/H synthase 2 Inhibito... 1 1
Fructose-1,6-bisphosphatase 1 Inhibitor 1-(4-aminophenylsulfon... 2 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 6
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 5 10
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 7 2
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-158324 Family 1 1
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
Prostaglandin G/H synthase 1 Inhibitor 4-amino-n-(2-chlorophen... 2 3
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 2
Gamma-aminobutyric acid receptor Ligand Toluene-1-diazonium-3-... 1 1
Carbonic anhydrase Inhibitor 4-amino-3-fluoro-5-iodobenzenesul... 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Thiour... 3 14
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-(met... 4 1
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2,2,3,... 2 1
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 5
Thyroid hormone receptor beta and Beta-lactamase ligand CHEMBL... 1 3
Neprilysin inhibitor AGN-PC-047EOR family 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 3n2p ... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1-(2-c... 1 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 2 0
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor (1E)-... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor (2Z)-... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 5
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor ST510... 7 3
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 4 31
Beta-lactamase inhibitor 3-(4-BENZENESULFONYL-THIOPHENE-2-SULF... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-amin... 1 0
Coagulation factor XIII A chain and Protein-glutamine gamma-gl... 2 3
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor AGN-PC... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1,2,3,... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00102329 DAP001191 Approved Drug Sulfacetamide
CFAMM00102317 DNC005752 Investigative Drug N-(4-Sulfamoyl-phenyl)-isobutyramide
CFAMM00102339 DNC005748 Investigative Drug ACETYLSULFANILAMIDE
CFAMM00102451 DNC004675 Investigative Drug 2-aminobenzenesulfonamide
CFAMM00102285 DNC004677 Investigative Drug 2-(N''-Acetyl-hydrazino)-benzenesulfonamide
CFAMM00102316 DNC005753 Investigative Drug Pentanoic acid (4-sulfamoyl-phenyl)-amide
CFAMM00102416 DNC013624 Investigative Drug 2-(4-aminophenylsulfonamido)acetic acid
CFAMM00102321 DNC005754 Investigative Drug 2,2-Dimethyl-N-(4-sulfamoyl-phenyl)-propionamide
CFAMM00102406 DNC007170 Investigative Drug 4-azidobenzenesulfonamide
CFAMM00102298 DNC003377 Investigative Drug 3-Mercuri-4-Aminobenzenesulfonamide
CFAMM00102320 DNC005756 Investigative Drug 4-Methanesulfonylamino-benzenesulfonamide
CFAMM00102439 DNC001391 Investigative Drug Sulfonamide
CFAMM00102289 DNC006830 Investigative Drug 3-mercapto-N-(4-sulfamoyl-phenyl)-propionamide
CFAMM00102319 DNC005750 Investigative Drug N-(4-Sulfamoyl-phenyl)-propionamide
CFAMM00102438 DNC004888 Investigative Drug 4-amino-3-fluorobenzenesulfonamide
CFAMM00102424 DNC004891 Investigative Drug 4-amino-3-iodobenzenesulfonamide
CFAMM00102318 DNC005751 Investigative Drug N-(4-Sulfamoyl-phenyl)-butyramide
CFAMM00102348 DNC004910 Investigative Drug 3-Amino-benzenesulfonamide
CFAMM00102340 DNC005749 Investigative Drug 2,2,2-Trifluoro-N-(4-sulfamoyl-phenyl)-acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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