CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Alpha-1 adrenergic receptor ligand sulfamoyl substituted phenethylamine derivative Tamsulosin family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00016593 Functional Category Approved Drug with Human Metabolite
Superfamily Alpha-1 adrenergic receptor ligand sulfamoyl substituted phenethylamine derivative Tamsulosin Superfamily
Class Class 77


External ID

Functional Category

Molecule Name

CFAMM00016593 DAP000086 Approved Drug Tamsulosin
CFAMM00016582 CHEMBL1630939 Bioactive 2-methoxy-5-[(2R)-2-[2-(2-phenylmethoxyphenoxy)ethylamino]propyl]benzenesulfonamide
CFAMM00016596 CHEMBL1630940 Bioactive 2-methoxy-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]benzenesulfonamide
CFAMM00016595 CHEMBL1630938 Bioactive 2-methoxy-5-[(2R)-2-[2-(2-propan-2-yloxyphenoxy)ethylamino]propyl]benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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