CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD804
Family Name Prothrombin Inhibitor Ximelagatran Family
No. of Seeds 5 No. of Other Members 48
Family Centroid CFAMM00102865 Functional Category Approved Drug with Human Metabolite
Superfamily Prothrombin Inhibitor Ximelagatran Superfamily
Class Class 608

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Prothrombin Inhibitor Efegatran Family 9 47
Prothrombin Inhibitor LB30812 Family 12 36
Neuromedin-K receptor Ligand Senktide Family 15 22
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor Sibrafiban Family 4 6
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anil... 1 2
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-6-[[2-(4... 2 11
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7301018... 4 3
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7961093... 1 0
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Prothrombin inhibitor (2S,3aS,7aS)-N-[(4-carbamimidoylphenyl)m... 8 7
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00102865 DAP001218 Approved Drug Ximelagatran
CFAMM00102886 CHEMBL207187 Bioactive 2-[[(2R)-1-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]pyrrolidin-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino]acetic acid
CFAMM00102867 CHEMBL206418 Bioactive 2-[[(2R)-1-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]-2,5-dihydropyrrol-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino]acetic acid
CFAMM00102854 CHEMBL207528 Bioactive 2-[[1-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]-2,5-dihydropyrrol-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino]acetic acid
CFAMM00102880 DNC006574 Investigative Drug MELAGATRAN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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