CFam Chemical Families Database
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CFam Family Information

CFAM Family ID CFFAD806
Family Name Renin Inhibitor Remikiren Family
No. of Seeds 100 No. of Other Members 126
Family Centroid CFAMM00103091 Functional Category Approved Drug with Natural Product
Superfamily Insulin-degrading enzyme inhibitor Bacitracin, Renin inhibitor Remikiren Superfamily
Class Class 414

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
Epidermal Growth Factor family 111 209
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Insulin receptor Ligand Insulin, Porcine Family 61 205
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Growth hormone receptor Ligand EP-51216 Family 34 390
NS5A protein Inhibitor Bms 790052 Family 5 9
CBP-501 family 7 8
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Renin Inhibitor Enalkiren Family 56 44
Caspase-9 Inhibitor Z-lehd-fmk Family 1 0
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Glycylpeptide N-tetradecanoyltransferase Inhibitor SC-58272 Fa... 2 11
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor AC1LAD48 family 19 5
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein and Protease inhibitor 161186-52-3 family 3 3
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-(4... 3 9
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Renin and Cathepsin D inhibitor tert-butyl N-[(2R)-1-[[3-[[(2R... 19 4
Renin and Pepsin A inhibitor tert-butyl N-[(2S)-1-[[2-[[(4S,5S... 4 0
Pol polyprotein inhibitor AC1LAQE0 family 13 4
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 6 2
Pol polyprotein inhibitor (2S)-4-(1H-benzimidazol-2-ylmethyl)-... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Renin and Pepsin A inhibitor [(2S)-1-[[(2R)-1-[[(2S,3R)-1-cycl... 2 2
Prolyl endopeptidase inhibitor SureCN8938520 family 2 1
Pol polyprotein inhibitor AC1LA3L0 family 3 2
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0
Oxytocin receptor and Vasopressin V2 receptor ligand (2S)-N-[(... 6 30
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 2
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 1 1
Renin inhibitor propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imid... 4 0
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-[[4-(2-... 5 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-h... 1 0
Renin inhibitor (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-im... 4 0
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Renin inhibitor (4S)-5-cyclohexyl-2,2-difluoro-4-[[(2S)-3-(1H-... 1 0
Renin inhibitor tert-butyl N-[1-[[1-[[1-cyclohexyl-4,4-difluor... 5 0
Gastrin-releasing peptide receptor ligand (2S)-N-[(2S)-1-[[(2S... 1 0
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-(3-imidazo... 1 0
Renin inhibitor tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4... 2 2
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3
Renin inhibitor [(2S)-1-[[(2R)-1-[[(2S,3S)-1-cyclohexyl-3-hydr... 1 0
Oxytocin receptor and Vasopressin V1a receptor ligand (2S)-N-[... 2 0
Oxytocin receptor and Vasopressin V1a receptor ligand 2-[3-[(1... 1 0
Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0
Neuropeptide Y receptor type 2 ligand CHEMBL411765 family 1 0
Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(2,4-difluor... 5 0
Histamine H3 receptor and Histamine H4 receptor ligand AGN-PC-... 1 2
Growth hormone secretagogue receptor type 1 ligand CHEMBL52599... 1 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16g... 1 0
Putative NP ZINC40309668 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00103091 DAP001220 Approved Drug Remikiren
CFAMM00103225 CHEMBL1783187 Bioactive AC1NQY7T
CFAMM00103071 CHEMBL306275 Bioactive (2E)-2-benzylidene-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-4-morpholin-4-yl-4-oxobutanamide
CFAMM00103191 CHEMBL382977 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-propan-2-ylsulfonylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103266 CHEMBL288411 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(6S)-2-oxo-1,3-oxazinan-6-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103113 CHEMBL288272 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-3-methyl-2-oxo-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103142 CHEMBL66934 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103218 CHEMBL416429 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-2-oxo-3-propan-2-yl-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103051 CHEMBL445350 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103064 CHEMBL61639 Bioactive (4S,5S)-5-[[2-[(2-acetamido-3-phenylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-cyclohexyl-4-hydroxy-N-(3-methylbutyl)-2-methylidenehexanamide
CFAMM00103093 CHEMBL29004 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2R,3S)-4-(azidomethyl)-1-cyclohexyl-3,4,5-trihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103184 CHEMBL289144 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-2-oxo-3-propan-2-yloxy-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103246 CHEMBL93418 Bioactive (2S)-2-tert-butylsulfonyl-N-[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-[2-(2-morpholin-4-ylethylamino)-2-oxoethyl]sulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-phenylpropanamide
CFAMM00103042 CHEMBL38955 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-3-methoxy-2-oxo-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103135 CHEMBL66213 Bioactive ethyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103070 CHEMBL52929 Bioactive (2S,5S)-5-[[(2S)-2-[[(2S)-2-benzyl-3-tert-butylsulfanylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-propan-2-ylhexanamide
CFAMM00103224 CHEMBL293196 Bioactive Cgp 38560
CFAMM00103204 CHEMBL65948 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103050 CHEMBL2347494 Bioactive (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
CFAMM00103099 CHEMBL357253 Bioactive 2-benzyl-3-tert-butylsulfonyl-N-[1-[[(2S,3R,4R,5R,6R)-1-cyclohexyl-3,4,5,6,7-pentahydroxyheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]propanamide
CFAMM00103128 CHEMBL58263 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-N'-[2-(2-methoxyethoxymethoxy)ethyl]-N'-methylbutanediamide
CFAMM00103190 CHEMBL408084 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2R,3R,4S)-4-(azidomethyl)-1-cyclohexyl-3,5-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103063 CHEMBL328736 Bioactive (2S)-2-benzyl-N-[(2S)-1-[[(2S,3R,4R)-5-(butylsulfamoyl)-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-tert-butylsulfonylpropanamide
CFAMM00103076 CHEMBL307917 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-4-phenylbutan-2-yl]morpholine-4-carboxamide
CFAMM00103141 CHEMBL299055 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-N'-[2-(methoxymethoxy)ethyl]-N'-methylbutanediamide
CFAMM00103183 CHEMBL289145 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-3-(2-methylpropyl)-2-oxo-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103121 CHEMBL280744 Bioactive N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]oxane-4-carboxamide
CFAMM00103134 CHEMBL554414 Bioactive N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3,3-dimethylbutanamide;hydrochloride
CFAMM00103147 CHEMBL288347 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(3S)-5-ethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103175 CHEMBL431771 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-(2-methylpropylsulfanyl)butan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103277 CHEMBL31019 Bioactive (1S,2S,3R)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-imidazol-1-yl-1-oxopropan-2-yl]-2-phenyl-3-propan-2-ylsulfonylcyclopropane-1-carboxamide
CFAMM00103049 CHEMBL2347495 Bioactive (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
CFAMM00103189 CHEMBL265485 Bioactive [(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl] morpholine-4-carboxylate
CFAMM00103264 CHEMBL305865 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxo-3-phenylbutan-2-yl]morpholine-4-carboxamide
CFAMM00103229 CHEMBL75510 Bioactive (2S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-[[2-hydroxyethyl(methyl)carbamoyl]amino]-3-phenylpropanamide
CFAMM00103153 CHEMBL297628 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-propan-2-ylsulfonylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3,3-dimethylbutanamide
CFAMM00103216 CHEMBL282757 Bioactive N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]morpholine-4-carboxamide
CFAMM00103257 CHEMBL440779 Bioactive N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-methylpropanamide
CFAMM00103146 CHEMBL288346 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-3-(2-hydroxyethyl)-2-oxo-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103040 CHEMBL75117 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]morpholine-4-carboxamide
CFAMM00103055 CHEMBL75683 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-hydroxypiperidine-1-carboxamide
CFAMM00103068 CHEMBL303076 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-N'-(2-methoxyethyl)-N'-methylbutanediamide
CFAMM00103097 CHEMBL66149 Bioactive N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3,3-dimethylbutanamide
CFAMM00103250 CHEMBL48722 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-5-[3-(dimethylamino)propoxycarbonylamino]-3-hydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103048 CHEMBL329808 Bioactive (2S)-2-[(4-aminopiperidin-1-yl)sulfonylmethyl]-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-pyridin-2-ylhexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-phenylpropanamide
CFAMM00103126 CHEMBL50966 Bioactive AGN-PC-073RJB
CFAMM00103188 CHEMBL304379 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylmethoxybutan-2-yl]carbamate
CFAMM00103202 CHEMBL315380 Bioactive (2S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanamide
CFAMM00103276 CHEMBL273771 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(4S)-1-ethyl-2-oxoimidazolidin-4-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103061 CHEMBL300468 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-3,5-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]-4-hydroxypiperidine-1-carboxamide
CFAMM00103215 CHEMBL301395 Bioactive propyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]propanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00103269 CHEMBL67107 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-methylsulfanylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103090 CHEMBL284451 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103181 CHEMBL347171 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[1-cyclohexyl-3-hydroxy-4-[3-methyl-1-(3-phenylpropanoylamino)butyl]sulfanylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103242 CHEMBL291119 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(2S,4S)-4-methyloxolan-2-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103208 CHEMBL50944 Bioactive AGN-PC-073RLA
CFAMM00103221 CHEMBL318672 Bioactive (2S)-2-benzyl-3-tert-butylsulfonyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-pyridin-2-ylhexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]propanamide
CFAMM00103054 CHEMBL61420 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-N'-(2-hydroxyethyl)-N'-methylbutanediamide
CFAMM00103132 CHEMBL297701 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-3-hydroxy-6-methyl-5-(propylcarbamoylamino)heptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103145 CHEMBL300724 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-cyclohexyl-5-ethylsulfonyl-3-hydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103173 CHEMBL143427 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-N'-[2-(2-methoxyethoxymethoxy)ethyl]-N'-methylbutanediamide
CFAMM00103235 CHEMBL52833 Bioactive (2S,5S)-5-[[(2S)-2-[[(2S)-2-benzyl-3-tert-butylsulfinylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-propan-2-ylhexanamide
CFAMM00103080 CHEMBL48481 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-3-hydroxy-6-methyl-5-(pentanoylamino)heptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103187 CHEMBL40053 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethoxy-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103201 CHEMBL299144 Bioactive AGN-PC-073RFU
CFAMM00103073 CHEMBL73712 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]piperazine-1-carboxamide
CFAMM00103138 CHEMBL267277 Bioactive (2S)-N-[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanamide
CFAMM00103164 CHEMBL43958 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-5-formamido-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103227 CHEMBL287953 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103115 CHEMBL292812 Bioactive (2S,5S)-5-[[(2S)-2-[(2-benzyl-5,5-dimethyl-4-oxohexanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-propan-2-ylhexanamide
CFAMM00103180 CHEMBL59883 Bioactive (4S,5S)-6-cyclohexyl-5-[[2-[[2-(3,3-dimethylbutanoylamino)-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-hydroxy-N-methyl-2-methylidenehexanamide
CFAMM00103268 CHEMBL357302 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103053 CHEMBL290605 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-2-oxo-3-propyl-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103066 CHEMBL299605 Bioactive 2-pyrrolidin-1-ylethyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]propanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00103131 CHEMBL38954 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103144 CHEMBL76458 Bioactive (2S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-(dimethylcarbamoylamino)-3-phenylpropanamide
CFAMM00103248 CHEMBL68859 Bioactive N-[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-(2-methylpropanoylamino)-3-phenylmethoxybutanamide
CFAMM00103079 CHEMBL430933 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103095 CHEMBL63482 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-4-cyclohexylsulfanyl-3-hydroxybutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103172 CHEMBL292677 Bioactive 2-[[3-[[(2S,3R,4R)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]-3-oxopropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
CFAMM00103200 CHEMBL66562 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-4-cyclohexylsulfonyl-3-hydroxybutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103213 CHEMBL345043 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-4-morpholin-4-yl-4-oxobutanamide
CFAMM00103261 CHEMBL48343 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-5-[2-(dimethylamino)ethoxycarbonylamino]-3-hydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103044 CHEMBL139813 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-4-(4-methylpiperazin-1-yl)-4-oxobutanamide
CFAMM00103124 CHEMBL347008 Bioactive 5-[[2-[[2-[(3-amino-3-methylbutanoyl)amino]-3-phenylpropanoyl]-methylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-cyclohexyl-4-hydroxy-N-(3-methylbutyl)-2-propan-2-ylhexanamide
CFAMM00103226 CHEMBL1783184 Bioactive AC1MQOLY
CFAMM00103072 CHEMBL306274 Bioactive N-[(Z)-3-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-oxo-1-phenylprop-1-en-2-yl]morpholine-4-carboxamide
CFAMM00103101 CHEMBL29315 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2R,3R)-4-azido-1-cyclohexyl-3-hydroxybutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103114 CHEMBL171319 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-1-cyclohexyl-3-hydroxy-6-methyl-5-[[(2S)-2-methylbutyl]carbamoyl]heptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103179 CHEMBL94677 Bioactive (2S)-2-[(4-aminocyclohexyl)sulfonylmethyl]-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-pyridin-2-ylhexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-phenylpropanamide
CFAMM00103065 CHEMBL74765 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]morpholine-4-carboxamide
CFAMM00103143 CHEMBL30495 Bioactive (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-imidazol-1-yl-1-oxopropan-2-yl]-2-phenyl-3-propan-2-ylsulfonylcyclopropane-1-carboxamide
CFAMM00103206 CHEMBL20841 Bioactive AGN-PC-00Q0BO
CFAMM00103219 CHEMBL300036 Bioactive ethyl N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-propan-2-ylsulfonylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103094 CHEMBL317370 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-[2-[(1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl)amino]-2-oxoethyl]sulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103185 CHEMBL289146 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-hydroxy-1-[(5S)-2-oxo-1,3-oxazolidin-5-yl]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00103212 CHEMBL291591 Bioactive A-62198
CFAMM00103273 CHEMBL306338 Bioactive (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-4-morpholin-4-yl-4-oxobutanamide
CFAMM00103198 CHEMBL92384 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-[2-(2-morpholin-4-ylethylamino)-2-oxoethyl]sulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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