CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Dihydropterin pyrophosphokinase-dihydropteroate synthase inhibitor benzenesulfonamide derivative Sulfamethazine Family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00103445 Functional Category Approved Drug
Superfamily Dihydropterin pyrophosphokinase-dihydropteroate synthase inhibitor benzenesulfonamide derivative Sulfadiazine Sulfamethazine Superfamily
Class Class 600

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 2
Carbonic anhydrase 12 and Carbonic anhydrase 14 inhibitor 2-[[... 8 8
Carbonic anhydrase 2 and Carbonic anhydrase 7 inhibitor 4-[(4,... 5 4
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Histone-lysine N-methyltransferase 2A and Huntingtin inhibitor... 1 0


External ID

Functional Category

Molecule Name

CFAMM00103445 DAP001241 Approved Drug Sulfamethazine
CFAMM00103426 CHEMBL46071 Bioactive Ro 63-0563
CFAMM00103440 DNC003568 Investigative Drug Ro-63-0563
CFAMM00103427 DNC003597 Investigative Drug Ro-04-6790

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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