CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD829
Family Name 14-alpha sterol demethylase Inhibitor Butoconazole Family
No. of Seeds 2 No. of Other Members 53
Family Centroid CFAMM00104327 Functional Category Approved Drug
Superfamily 14-alpha sterol demethylase Inhibitor Butoconazole Superfamily
Class Class 626

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
Benzodiazepine receptor Ligand Midazolam Family 5 160
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
HCV NS4B protein Inhibitor Clemizole Family 2 43
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(1-(4-thi... 3 36
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Aromatase Inhibitor 1-(2-(benzo[b]thiophen-4-yl)ethyl)-1h-imid... 1 1
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 6 6
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(4-nitrob... 3 5
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(3,4-dich... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 6
Aromatase inhibitor AGN-PC-075MV1 family 1 3
Histamine H3 receptor ligand SureCN1382602 family 6 0
Progesterone receptor and Cytochrome P450 2C19 ligand AGN-PC-0... 8 3
Heme oxygenase 1 and Heme oxygenase 2 inhibitor 1-imidazol-1-y... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00104327 DAP001267 Approved Drug Butoconazole
CFAMM00104337 DNC013122 Investigative Drug 1-(3-(4-chlorophenyl)propyl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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