CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD83
Family Name Progesterone receptor ligand steroid Mifepristone family
No. of Seeds 14 No. of Other Members 75
Family Centroid CFAMM00017032 Functional Category Approved Drug with Natural Product
Superfamily Progesterone receptor ligand steroid Mifepristone Superfamily
Class Class 81

Cousin Family NamesSeedsMembers
Glucocorticoid receptor Ligand A-348441 Family 21 4
Progesterone receptor and Glucocorticoid receptor ligand SureC... 18 4
Glucocorticoid receptor ligand 4-[[2-[4-[(8S,11R,13S,14S,17S)-... 6 1
Glucocorticoid receptor and Progesterone receptor ligand (4R)-... 2 3
Progesterone receptor ligand tert-butyl (2S)-2-[6-[[[4-[(8S,11... 3 0
Progesterone receptor and Glucocorticoid receptor ligand SureC... 1 0
Progesterone receptor and Glucocorticoid receptor ligand SureC... 1 0
Progesterone receptor ligand 3-(4-chlorophenyl)-1-[4-[(8S,11R,... 2 0
Progesterone receptor and Glucocorticoid receptor ligand CHEMB... 2 4
Progesterone receptor ligand (8S,11S,13S,14S,17S)-11-chloro-11... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00017035 DAP001554 Approved Drug Ulipristal
CFAMM00017032 DAP000090 Approved Drug Mifepristone
CFAMM00017036 CHEMBL258861 Bioactive (8R,9S,11S,13S,14S,17R)-11-[4-(dimethylamino)phenyl]-13-methyl-3'-methylidenespiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,2'-oxolane]-3-one
CFAMM00016979 CHEMBL504799 Bioactive methyl 6-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]hexanoate
CFAMM00017041 CHEMBL450052 Bioactive methyl 11-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]undecanoate
CFAMM00017019 CHEMBL499452 Bioactive methyl 8-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]octanoate
CFAMM00017048 CHEMBL444027 Bioactive 11-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]undecanoic acid
CFAMM00016997 CHEMBL510869 Bioactive 8-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]octanoic acid
CFAMM00016982 CHEMBL452860 Bioactive 6-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]hexanoic acid
CFAMM00017046 CHEMBL454224 Bioactive methyl 6-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]-6-oxohexanoate
CFAMM00017024 CHEMBL455175 Bioactive methyl 3-[4-[(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-11-yl]-N-methylanilino]propanoate
CFAMM00017039 DNCL002514 Clinical Trial Drug Telapristone
CFAMM00017017 DNC003727 Investigative Drug ONAPRISTONE
CFAMM00017031 DNC008403 Investigative Drug ULIPRISTAL ACETATE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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