CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00104690 Functional Category Approved Drug with Human Metabolite
Superfamily NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
Bucladesine family 1 1
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
TG-C family 11 208
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Selenazole-... 2 1
2-5A-dependent ribonuclease inhibitor [[(2R,3R,4R,5R)-5-(6-ami... 13 25


External ID

Functional Category

Molecule Name

CFAMM00104690 DAP001291 Approved Drug NADH
CFAMM00104697 DPR000034 Investigative Drug CYT-009-GhrQb
CFAMM00104692 DNC000982 Investigative Drug NADPH
CFAMM00104691 DNC002927 Investigative Drug P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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