CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD842
Family Name Cytochrome P450 2D6 Inhibitor Glutethimide Family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00104813 Functional Category Approved Drug
Superfamily Aromatase inhibitor Aminoglutethimide, CYP2D6 inhibitor Glutethimide Superfamily
Class Class 478

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Sodium channel protein type 5 subunit alpha Ligand Indecainide... 2 41
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 1 3
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 3 1
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00104813 DAP001305 Approved Drug Glutethimide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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