CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Folate receptor gamma Ligand Folic Acid Family
No. of Seeds 4 No. of Other Members 100
Family Centroid CFAMM00107561 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Folate receptor, Peptide deformylase binding Folic Acid analogs Superfamily
Class Class 639

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Prothrombin Inhibitor Dabigatran Family 7 182
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 11
Cholecystokinin receptor type A ligand A-65186 family 2 6
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 11
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 4
Dihydrofolate reductase and Thymidylate synthase inhibitor 2-[... 10 5
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Thymidylate synthase inhibitor AGN-PC-0757PM family 1 0
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Caspase-1 inhibitor (3S)-4-oxo-3-[[6-[[4-(quinoxalin-2-ylamino... 5 6
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 1
Integrin beta-1 and Integrin alpha-4 inhibitor (5R)-5-[[(2R)-2... 2 3
Folylpolyglutamate synthase, mitochondrial and Dihydrofolate r... 3 0
Dihydrofolate reductase inhibitor 2-[[4-[2-(2-amino-4-oxo-1,5,... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-4-methy... 2 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-(2-aminoethyl)pipe... 17 2
P2Y purinoceptor 12 inhibitor (4S)-4-[[6-[4-[2-(methylamino)-2... 51 8
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Thymidylate synthase and Dihydrofolate reductase inhibitor (2S... 1 0


External ID

Functional Category

Molecule Name

CFAMM00107561 DAP001309 Approved Drug Folic Acid
CFAMM00107567 DNCL002585 Clinical Trial Drug EC20
CFAMM00107548 DNC007649 Investigative Drug folate gamma-hydroxamic acid
CFAMM00107563 DNC007651 Investigative Drug folate gamma-L-phenylalaninehydroxamic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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