CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD846
Family Name Food vacuoles Inhibitor Mefloquine Family
No. of Seeds 2 No. of Other Members 25
Family Centroid CFAMM00107597 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Food vacuoles Inhibitor Mefloquine Superfamily
Class Class 70

Cousin Family NamesSeedsMembers
Grt 6005/06 family 4 22
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
D(1B) dopamine receptor and D(2) dopamine receptor Ligand Flut... 1 6
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-... 3 6
Metabotropic glutamate receptor 5 Ligand 2-phenylethynyl-5,6,7... 1 4
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 3 9
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta inhibit... 2 7
3-methyl-2-(quinolin-2-ylmethyl)-2H-furan-5-one NP 4-methyl-5-... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00107597 DAP001310 Approved Drug Mefloquine
CFAMM00107607 DNC008466 Investigative Drug phenyl(2-(trifluoromethyl)quinolin-4-yl)methanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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