CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD870
Family Name Multidrug resistance-associated protein 1 Inhibitor Biricodar Family
No. of Seeds 6 No. of Other Members 40
Family Centroid CFAMM00109150 Functional Category Approved Drug with Natural Product
Superfamily Multidrug resistance-associated protein 1 Inhibitor Biricodar Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Glucokinase Inhibitor GKA1 Family 2 67
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Renin Inhibitor CP-305202 Family 9 30
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 1 10
cGMP-specific 3',5'-cyclic phosphodiesterase and Cytochrome P4... 5 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 7
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 7 2
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 1 18
Neutrophil elastase and Beta-lactamase inhibitor ST073523 family 1 0
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 2 2
NP 5-((4-chlorobenzyl)oxy)-2-(6,7-dimethoxy-1,2,3,4-tetrahydro... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00109150 DAP001352 Approved Drug Biricodar
CFAMM00109164 CHEMBL151841 Bioactive (1-phenyl-7-pyridin-2-ylheptan-4-yl) 1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate
CFAMM00109180 CHEMBL539357 Bioactive AGN-PC-07C2VV
CFAMM00109149 CHEMBL150120 Bioactive AGN-PC-02XZMU
CFAMM00109145 CHEMBL151727 Bioactive AGN-PC-02YBHN
CFAMM00109129 DNC002707 Investigative Drug FKB-001

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27037 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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