CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD875
Family Name Serum albumin Inhibitor Ebselen Family
No. of Seeds 3 No. of Other Members 62
Family Centroid CFAMM00109250 Functional Category Approved Drug with Natural Product
Superfamily Serum albumin Inhibitor Ebselen Superfamily
Class Class 545

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Voltage-gated sodium channel Ligand Oxcarbazepine Family 1 4
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
HT-2157 family 1 3
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Epidermal growth factor receptor Ligand 5,6-bis-p-tolylamino-i... 2 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-... 1 4
Fatty acid-binding protein and C-X-C chemokine receptor type 1... 1 6
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Transient receptor potential cation channel subfamily V member... 6 33
Liver carboxylesterase 1 Inhibitor 6-bromo-5-methyl-1h-indole-... 1 0
Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dion... 3 7
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Liver carboxylesterase 1 Inhibitor 7-(trifluoromethyl)-1h-indo... 1 1
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Transient receptor potential cation channel subfamily V member... 1 5
Progesterone receptor Ligand 3-(3,3-dimethyl-2-oxoindolin-5-yl... 2 10
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
M-phase inducer phosphatase 1 Inhibitor (z)-2-(1-decyl-2-oxoin... 2 2
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Muscarinic acetylcholine receptor M5 Ligand VU0119498 Family 1 3
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Fatty-acid amide hydrolase 1 Inhibitor 1-biphenyl-4-ylmaleimid... 2 11
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 5
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Androgen receptor ligand SureCN13483375 family 3 2
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
4,4,6,9-tetramethyl-6-phenyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]q... 5 1
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00109250 DAP001372 Approved Drug Ebselen
CFAMM00109254 DNC007986 Investigative Drug 2-(2-hexylphenyl)isoindoline-1,3-dione
CFAMM00109267 DNC007182 Investigative Drug 1-phenyl-1H-indole-2,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27261 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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