CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD88
Family Name u-type opioid receptor ligand opiate opiate analog Oxymorphone Family
No. of Seeds 22 No. of Other Members 105
Family Centroid CFAMM00017456 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily opioid receptor ligand opiate Codeine Buprenorphine Oxymorphone Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Nalfurafine Hcl family 33 107
ALKS33 family 3 10
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 2 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 32 30
Delta-type opioid receptor Ligand 6-cinnamoyl-n-methylstephasu... 3 0
Delta-type opioid receptor Ligand Longanine Family 3 0
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 5 11
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 13 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Mu-type opioid receptor ligand Morphine-6-glucuronide family 7 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 6 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 9 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Gastrin/cholecystokinin type B rec... 1 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00017568 DAP000379 Approved Drug Naltrexone
CFAMM00017452 DAP000253 Approved Drug Hydrocodone
CFAMM00017478 DAP000283 Approved Drug Oxycodone
CFAMM00017456 DAP001138 Approved Drug Oxymorphone
CFAMM00017581 DAP000097 Approved Drug Naloxone
CFAMM00017529 DAP000472 Approved Drug Hydromorphone
CFAMM00017580 DNAP001296 Approved Drug Methylnaltrexone bromide
CFAMM00017566 CHEMBL540269 Bioactive (4aS,7aR,12bS)-9-hydroxy-4a-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrobromide
CFAMM00017523 CHEMBL278717 Bioactive (4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-ethoxy-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00017535 DCL000881 Clinical Trial Drug Methylnaltrexone
CFAMM00017471 DNC009670 Investigative Drug 14-O-phenylpropylnaltrexone
CFAMM00017480 DNC014097 Investigative Drug SPIROINDANYLOXYMORPHONE
CFAMM00017515 DNC013698 Investigative Drug N-isobutylnoroxymorphone
CFAMM00017431 DNC009078 Investigative Drug Naltrexone methiodide
CFAMM00017565 DNC011358 Investigative Drug NALTREXONE HYDROCHLORIDE
CFAMM00017557 DNC003486 Investigative Drug N-Methylnaloxonium
CFAMM00017475 DNC008422 Investigative Drug MORPHINONE
CFAMM00017483 DNC000101 Investigative Drug 7-benzylidenenaltrexone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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