CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD904
Family Name Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Inhibitor Tyverb/tykerb Family
No. of Seeds 3 No. of Other Members 140
Family Centroid CFAMM00112333 Functional Category Approved Drug
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Inhibitor Tyverb/tykerb Superfamily
Class Class 678

Cousin Family NamesSeedsMembers
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Vascular endothelial growth factor receptor 1 and Vascular end... 6 28
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-2... 7 1
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Rho-associated protein kinase 2 inhibitor SureCN3232097 family 1 1
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN72661... 3 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-6... 7 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor AGN-PC-074D... 4 0
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN14736... 4 0
Inosine-5'-monophosphate dehydrogenase 2 inhibitor AC1LAY14 fa... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00112333 DAP001451 Approved Drug Tyverb/Tykerb
CFAMM00112440 CHEMBL25138 Bioactive SureCN1474014
CFAMM00112455 DNC006469 Investigative Drug 3-methoxy-4-(oxazol-5-yl)aniline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44592 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543