CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Growth hormone receptor Ligand Ibutamoren Family
No. of Seeds 7 No. of Other Members 41
Family Centroid CFAMM00112653 Functional Category Approved Drug
Superfamily Growth hormone receptor Ligand Ibutamoren Superfamily
Class Class 688

Cousin Family NamesSeedsMembers
Substance-K receptor and Neuromedin-K receptor ligand 1-benzyl... 3 10
Substance-P receptor ligand N-[2-[4-[(2S)-2-(benzylamino)-3-[(... 2 0
Growth hormone secretagogue receptor type 1 ligand N-[6-[[2-[1... 1 0
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 1 0


External ID

Functional Category

Molecule Name

CFAMM00112653 DAP001483 Approved Drug Ibutamoren
CFAMM00112641 CHEMBL55240 Bioactive (2S)-2-(benzylamino)-3-[(4-chlorophenyl)methoxy]-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)propan-1-one
CFAMM00112640 CHEMBL51794 Bioactive (2S)-2-(benzylamino)-3-[(3-chlorophenyl)methoxy]-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)propan-1-one
CFAMM00112648 CHEMBL301259 Bioactive (2S)-2-[(2-aminoacetyl)amino]-3-hydroxy-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;2,2,2-trifluoroacetic acid
CFAMM00112669 CHEMBL542653 Bioactive 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;hydrochloride
CFAMM00112658 CHEMBL53312 Bioactive (2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)propan-1-one
CFAMM00112677 CHEMBL294324 Bioactive [(2R)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-3-oxopropyl] octanoate;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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