CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Omega 1 Benzodiazepine receptor Ligand Indiplon Family
No. of Seeds 4 No. of Other Members 25
Family Centroid CFAMM00112693 Functional Category Approved Drug
Superfamily Omega 1 Benzodiazepine receptor Ligand Indiplon Superfamily
Class Class 689

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand Ocinaplon Family 1 10
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 26
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
Aurora kinase A and Aurora kinase B inhibitor 4-amino-N-[4-(th... 1 1
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(1-methylin... 4 1
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(4-imidazol... 1 0
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Probable G-protein coupled receptor 142 ligand 5-butyl-N-[(3-m... 4 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Platelet-activating factor receptor ligand 1,8-dimethyl-5-[4-(... 1 0
MAP kinase-activated protein kinase 2 and Cyclin-dependent kin... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand thioph... 2 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-07C04Y... 1 3


External ID

Functional Category

Molecule Name

CFAMM00112693 DAP001484 Approved Drug Indiplon
CFAMM00112683 CHEMBL2409031 Bioactive 1-(5-methyl-4-thiophen-2-ylpyrimidin-2-yl)-5-propyl-N-(2-pyridin-4-ylpropan-2-yl)pyrazole-4-carboxamide
CFAMM00112695 CHEMBL2409027 Bioactive 5-butyl-1-(5-methyl-4-thiophen-2-ylpyrimidin-2-yl)-N-(pyridin-4-ylmethyl)pyrazole-4-carboxamide
CFAMM00112706 DCL000696 Clinical Trial Drug Amitriptyline+ketamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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