CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD921
Family Name Muscarinic acetylcholine receptor Ligand Mebeverine Family
No. of Seeds 2 No. of Other Members 27
Family Centroid CFAMM00113125 Functional Category Approved Drug with Natural Product
Superfamily Muscarinic acetylcholine receptor Ligand Mebeverine Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Endothelin-1 receptor Ligand PD156707 Family 41 211
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Fatty-acid amide hydrolase 1 Inhibitor 4-(cyclohexylmethylcarb... 2 4
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Acetylcholinesterase Inhibitor Taspine Family 1 0
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Histamine H3 receptor ligand 1-(3,4-dimethoxyphenyl)-4-(4-pent... 2 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor 2-[4-... 3 2
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 4 3
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00113125 DAP001494 Approved Drug Mebeverine
CFAMM00113135 DNC001626 Investigative Drug Dilazep

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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