CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD922
Family Name Insulin receptor Ligand Meglitinides Family
No. of Seeds 9 No. of Other Members 25
Family Centroid CFAMM00113171 Functional Category Approved Drug with Natural Product
Superfamily Insulin receptor Ligand Meglitinides Superfamily
Class Class 691

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Nemonapride Family 70 283
D(2) dopamine receptor Ligand Remoxipride Family 12 84
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
D(2) dopamine receptor Ligand Epidepride Family 31 66
D(2) dopamine receptor ligand (E)-2,3-dihydroxybut-2-enedioic ... 6 10
D(2) dopamine receptor ligand 2-bromo-3-chloro-N-[[(2S)-1-ethy... 1 1
D(2) dopamine receptor ligand 2-chloro-3-ethyl-N-[[(2S)-1-ethy... 3 0
D(2) dopamine receptor ligand 2-bromo-N-[[(2S)-1-ethylpyrrolid... 3 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
D(2) dopamine receptor ligand AGN-PC-0041GL family 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
C-C chemokine receptor type 3 ligand N-[(3R)-1-[(6-fluoronapht... 1 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00113171 DAP001495 Approved Drug Meglitinides
CFAMM00113154 CHEMBL1907692 Bioactive 3-chloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-5,6-dimethoxybenzamide
CFAMM00113169 CHEMBL350287 Bioactive 5-chloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxy-3-propylbenzamide
CFAMM00113160 CHEMBL161973 Bioactive 5-chloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxy-3-methylbenzamide
CFAMM00113149 CHEMBL171921 Bioactive 3,5-dichloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2,6-dimethoxybenzamide
CFAMM00113142 CHEMBL173536 Bioactive AGN-PC-0041GN
CFAMM00113147 CHEMBL1276712 Bioactive 3-chloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-hydroxy-2,6-dimethoxybenzamide
CFAMM00113155 CHEMBL366766 Bioactive N-(1-benzylpiperidin-4-yl)-3,5-dichloro-2-hydroxy-6-methoxybenzamide
CFAMM00113141 DNC011796 Investigative Drug ETICLOPRIDE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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