CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD930
Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Simvistatin Family
No. of Seeds 4 No. of Other Members 27
Family Centroid CFAMM00113269 Functional Category Approved Drug
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Simvistatin Superfamily
Class Class 697

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Pan-DAC Inhibitor AR-42 Family 21 153
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Transient receptor potential cation channel subfamily V member... 6 33
Dual specificity mitogen-activated protein kinase kinase 1 Inh... 1 1
Androgen receptor Ligand 6-n-propyl -4-trifluoromethylquinolin... 29 13
Dihydroorotate dehydrogenase (quinone), mitochondrial and Dihy... 1 2
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 0
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 1
Metabotropic glutamate receptor 2 ligand 4-[4-(methylamino)phe... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00113269 DAP001519 Approved Drug Simvistatin
CFAMM00113287 DCL000314 Clinical Trial Drug Teriflunomide
CFAMM00113300 DPR000045 Investigative Drug FK778
CFAMM00113272 DNC001240 Investigative Drug RS-61980

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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