CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD946
Family Name Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid receptor 2 Ligand Vitamin B3 Family
No. of Seeds 4 No. of Other Members 45
Family Centroid CFAMM00113947 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid receptor 2 Ligand Vitamin B3 Superfamily
Class Class 710

Cousin Family NamesSeedsMembers
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Farnesyl pyrophosphate synthase Inhibitor Risedronate Family 4 28
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 1 3
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Isoqui... 1 6
Metabotropic glutamate receptor 5 Ligand 6-phenylethynyl-nicot... 2 26
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Thromboxane-A synthase inhibitor (Z)-2-bromo-3-[4-(pyridin-3-y... 1 0
Glycine receptor subunit alpha-1 ligand [(1R,5R)-8-azabicyclo[... 2 10
Aromatase and Steroid 17-alpha-hydroxylase/17,20 lyase inhibit... 1 0
Muscarinic acetylcholine receptor M5 and Muscarinic acetylchol... 1 2
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1
Amino Acids and Derivatives Metabolite 3-Hydroxypicolinic acid... 1 2
2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopen... 5 0
NP (2-methyl-5-(prop-1-en-2-yl)cyclopent-1-en-1-yl)methyl Ison... 2 0
6-pyridin-3-ylpyran-2-one NP 6-(pyridin-3-yl)-2h-pyran-2-one F... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00113947 DAP001546 Approved Drug Vitamin B3
CFAMM00113954 DNCL001908 Clinical Trial Drug Laropiprant/niacin/ simvastatin combination
CFAMM00113923 DNC002987 Investigative Drug Quinolinic Acid
CFAMM00113942 DNC012538 Investigative Drug ISONICOTINIC ACID

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46003 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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