CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD955
Family Name Smoothened homolog Inhibitor Vismodegib Family
No. of Seeds 1 No. of Other Members 19
Family Centroid CFAMM00114344 Functional Category Approved Drug
Superfamily Smoothened homolog Inhibitor Vismodegib Superfamily
Class Class 718

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Neuromedin-K receptor Ligand SB222200 Family 17 235
ABC294640 family 5 75
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Transient receptor potential cation channel subfamily V member... 6 23
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Peroxisome proliferator-activated receptor delta Ligand GSK-37... 1 10
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 2-(4-... 1 1
Cannabinoid receptor 2 ligand 1-(benzenesulfonyl)-N-quinolin-3... 2 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-(3... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
C-X-C chemokine receptor type 2 ligand 6-chloro-N-(4-fluorophe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00114344 DNAP001262 Approved Drug Vismodegib

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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