CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD96
Family Name Nicotinic acetylcholine receptor alpha subunit Ligand benzylisoquinolinium derivative Doxacurium Family
No. of Seeds 4 No. of Other Members 18
Family Centroid CFAMM00019106 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Nicotinic acetylcholine receptor ligand bisbenzyltetrahydroisoquinolinium Superfamily
Class Class 92

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Cisatracurium Besylate... 1 0
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Cytochrome P450 3A4 Inhibitor 1,2-diacetoxylycorine Family 4 19
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
D(2) dopamine receptor Ligand (s)-secoantioquine Family 1 10
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00019077 DAP000105 Approved Drug Atracurium
CFAMM00019106 DAP000355 Approved Drug Doxacurium
CFAMM00019104 DAP000350 Approved Drug Doxacurium chloride
CFAMM00019143 DAP000716 Approved Drug Mivacurium

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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