CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (3S)-4-[2-[1-(4-fluorophenyl)-3-propan-2-ylindol-2-yl]ethynyl-hydroxyphosphoryl]-3-hydroxybutanoic acid family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00307149 Functional Category Bioactive
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (3S)-4-[2-[1-(4-fluorophenyl)-3-propan-2-ylindol-2-yl]ethynyl-hydroxyphosphoryl]-3-hydroxybutanoic acid Superfamily
Class Class 327

Cousin Family NamesSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Fluv... 6 53


External ID

Functional Category

Molecule Name

CFAMM00307152 CHEMBL99700 Bioactive (3S)-4-[2-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]ethynyl-hydroxyphosphoryl]-3-hydroxybutanoic acid
CFAMM00307149 CHEMBL101621 Bioactive (3S)-4-[2-[1-(4-fluorophenyl)-3-propan-2-ylindol-2-yl]ethynyl-hydroxyphosphoryl]-3-hydroxybutanoic acid
CFAMM00307154 CHEMBL102145 Bioactive (3S)-4-[[(E)-2-[1-(4-fluorophenyl)-3-propan-2-ylindol-2-yl]ethenyl]-hydroxyphosphoryl]-3-hydroxybutanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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